As with previous rounds, the competition continues with its straight knockout format, with teams playing each other over two legs.
Participating teams will have some time to wait before resuming the competition, as the EHF European Cup will take a break during the Men's EHF EURO 2024.
The first leg ties of the last 16 will take place on 10/11 February 2024, with the second legs on 17/18 February 2024.
Teams from 12 different countries make up the 16 teams left in the competition, including participants from recent editions of the EHF Champions League, Slovakia's TATRAN Presov and Besiktas Safi Cimento of Türkiye.
The teams are split into two pots, Pots 1 and 2. Each team from Pot 1 will be drawn against a team from Pot 2. The pots are as follows;
POT 1
Bregenz Handball (AUT)
HCB Karvina (CZE)
Olympiacos SFP (GRE)
FH Hafnarfjordur (ISL)
CS Minaur Baia Mare (ROU)
MRK Krka (SLO)
RK Metaloplastika Elixir Sabac (SRB)
Besiktas Safi Cimento (TUR)
POT 2
Förthof UHK Krems (AUT)
RK Sloboda (BIH)
RK Vogošca (BIH)
FTC-Green Collect (HUN)
Valur (ISL)
SSV Brixen (ITA)
CSA Steaua Bucuresti (ROU)
TATRAN Presov (SVK)
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