SU ZRK Crvena Zvezda (SRB) vs HSG Blomberg-Lippe (GER) 28:26 (15:13)
Blomberg-Lippe win (65:52) on aggregate
The Belgrade-based club was determined to make life hard for Blomberg-Lippe and to end the European journey on a high in front of the home supporters. Unlike the first leg, Crvena Zvezda did not trail once in the return leg and the Red and Whites were even up by six goals (11:5) in the 17th minute, which turned on the alarm within the visiting squad. However, the Bundesliga club did not let the motivated hosts rush into a bigger lead in the second half and Blomberg-Lippe slowed down the tempo as well and narrowed down the difference, with Melanie Veith making 11 saves in the process. Aleksandra Stamenic displayed a perfect performance as the left wing scored seven goals from seven attempts and Crvena Zvezda's squad leaves the EHF's second-tier club competition with a win, while Blomberg-Lippe will meet TUSSIES Metzingen in the German derby for a place in the group stage.
Armada Praxis Yalikavaspor (TUR) vs KPR Gminy Kobierzyce (POL) 26:27 (16:12)
Kobierzyce win (63:53) on aggregate
The reigning Turkish champions started the match on the front foot and Yalikavaspor were determined to narrow down Kobierzyce's nine-goal lead from the first leg. Furthermore, the encouraged hosts took a six-goal lead (10:4) in the 14th minute, which increased their hopes of mounting a comeback in the tie. However, the Polish club's performance improved after the break, both defensively and offensively, as Marcelina Polanska and her teammates crushed Yalikavaspor's dreams, when they took a lead (23:22) of their own in the 47th minute. The Özcan Kivanc-led squad failed to regain their lead until the final whistle, as Kobierzyce celebrated a second win in the tie, with the goalkeepers from both clubs Anca Mihaela Rombescu and Patrycja Chojnacka, respectively, making 10 saves each.
HC Gjorche Petrov-WHC Skopje (MKD) vs H 65 Höörs HK (SWE) 26:19 (13:12)
Höörs win (48:47) on aggregate
The Skopje-based club's intentions to mount a comeback became clear in the opening half as Gjorche Petrov's players bravely fought for every ball and displayed an inspired performance to take a minimal one-goal lead (13:12) at the break. However, the ambitious hosts additionally upped the tempo in the second half and Sime Simovski's squad came within a touching distance of Höörs' advantage in the final ten minutes of the match, with only three goals separating (22:17) the sides in the tie. With 60 seconds to go on the clock, Gjorche Petrov even took a six-goal lead (24:18), but unfortunately for them, they ran out of time and finished the match just one goal short of Höörs in the tie. The experienced right back Ivana Dežic ended the return leg as the top scorer with 10 goals in the net, but Höörs' goalkeeper Josefine Hultberg Dahlgren made an incredible 19 saves and played a pivotal role in helping her teammates secure a ticket to qualification round 3.
HC DAC Dunajská Streda (SVK) vs SCM Ramnicu Valcea (ROU) 26:33 (14:15)
Valcea win (61:52) on aggregate
The Romanian club held a two-goal advantage going into the return leg, but Dunajská Streda wasted no time in exceeding Valcea's lead, as the motivated hosts took a five-goal (9:4) advantage of their own in the 14th minute. With that being said, Bent Dahl's squad looked like they were losing control of the match, but Valcea improved massively ahead of the break to fully return in the tie and to take a narrow lead at half-time. In the second half, Dunajská Streda tried to regain the lead in the tie once again, but Nathalie Hagman and her team denied their attempts and celebrated a win, as well as their progress to qualification round 3. Experienced Hagman ended the match as the top scorer with 10 goals to her name, while Emma Boada Coronado (seven) and Eliška Desortová (eight) combined for 15 goals in the hosts' squad.